Which statement best assesses the impact of the cases Marbury v. Madison and McCulloch v. Maryland on the constitution.

The impact of Marbury v. Madison and McCulloch v. Maryland on the constitution is significant as they established important principles of judicial review and federal supremacy, respectively. Marbury v. Madison confirmed the power of the Supreme Court to review and declare acts of Congress unconstitutional, while McCulloch v. Maryland upheld the supremacy of federal laws over state laws. These cases have shaped the relationship between the three branches of government and have had a lasting impact on the interpretation and application of the Constitution.