Which of the following mutations would be most likely to have a harmful effect on an organism?(1 point)

Responses

all mutations have harmful effects on organisms
all mutations have harmful effects on organisms

a substitution of a thymine for an adenine
a substitution of a thymine for an adenine

a deletion of 3 bases near the center of a gene
a deletion of 3 bases near the center of a gene

there is not enough information to know whether a mutation would be harmful

a deletion of 3 bases near the center of a gene