Mutations can be beneficial, neutral, or harmful in an organism, changing their fitness in a population. Which of these scenarios model how mutations can be detrimental to an organism

A school of fish has an individual with increased gill surface for gas exchanges
A clutch of turtles has an individual with a reduce shell hardness
A litter of six kittens has one kitten that exhibits blue eye color
A litter of lion cubs is born with claws that do not retreat. Allowing faster running speeds.

A clutch of turtles has an individual with reduced shell hardness. This mutation would make the turtle more vulnerable to predators and decrease its chances of survival, making it detrimental to the organism.