Hemophilia is a hereditary bleeding disorder that primarily affects males. In 3-5 sentences, summarize why this condition typically affects males more than females. (4 points)
Hemophilia is primarily caused by a mutation in the genes responsible for producing blood clotting proteins, such as factor VIII or IX. These genes are located on the X chromosome, and males have only one copy of this chromosome, while females have two. If a male inherits the mutated gene, he will develop hemophilia, as he does not have a second copy to compensate for the deficiency. In contrast, females have two X chromosomes, so even if one carries the mutation, the other can still produce enough clotting factors to prevent the symptoms of hemophilia.
