Simplify the following expression by combining like terms:

`-7\left(n+3\right)-8\left(1+8n\right)-6m`

To simplify the expression, we multiply each term inside the parentheses with the coefficient outside the parentheses.

Starting with the first term:

-7(n+3) = -7n - 21

Next, the second term:

-8(1+8n) = -8 - 64n = -8 - 64n

Finally, we have the term -6m.

Combining all the simplified terms, we have:

-7n - 21 - 8 - 64n - 6m

Simplifying further, we can combine the like terms -7n and -64n:

-71n - 29 - 6m

To simplify the given expression:

We will start by distributing the negative 7 to the terms inside the first parentheses and the negative 8 to the terms inside the second parentheses.

`-7(n + 3) - 8(1 + 8n) - 6m`

Expanding the first parentheses:

`-7n - 7(3) - 8(1 + 8n) - 6m`

`-7n - 21 - 8(1 + 8n) - 6m`

Expanding the second parentheses:

`-7n - 21 - 8(1) - 8(8n) - 6m`

`-7n - 21 - 8 - 64n - 6m`

Combining like terms:

`(-7n - 64n) + (-21 - 8) - 6m`

`-71n - 29 - 6m`

Therefore, the simplified expression is `-71n - 29 - 6m`.