Give the structures, chemical name and use of one compound from each classification the histamine H1 receptors antagonist?
1. Cetirizine:
- Chemical name: (±) -[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride
- Use: Cetirizine is an antihistamine used to relieve symptoms of allergies such as hay fever, hives, and itching.
2. Loratadine:
- Chemical name: (R)-2-[4-[2-[4-(4-chlorophenyl)phenylmethoxy]ethyl]piperazin-1-yl]ethoxyacetic acid
- Use: Loratadine is an antihistamine used to treat symptoms of allergies such as itching, sneezing, and watery eyes.
3. Fexofenadine:
- Chemical name: ethyl (±)-4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl]benzoate
- Use: Fexofenadine is an antihistamine used to relieve symptoms of seasonal allergies such as runny nose, sneezing, and itchy/watery eyes.