Marfan syndrome is caused by mutations in the gene that provides instructions for making fibrillin-1, a protein that is an important component of connective tissue. These mutations can lead to problems with the growth and development of connective tissue, leading to the characteristic features of Marfan syndrome. In some cases, Marfan syndrome may be inherited from a parent who also has the condition, but in other cases, it may occur due to new mutations in the gene.
