Marfan syndrome is caused by a defect in FBN1 gene located on chromosome 15. The gene normally encodes the fibrilllin-1, which is important for the elasticity and appropriate growth of connective tissue. The defect in the gene that causes Marfan syndrome results in a decrease in the amount of functional fibrillin-1 produced. One defective copy of the gene is sufficient to cause Marfan syndrome.
Which of the following statements about Marfan syndrome is true?
A. It occurs more in males than in females.
B. It occurs because one healthy copy of the FBN1 gene does not produce enough fibrillin-1 to support normal connective tissue formation.
C. It only occurs in individuals who are homozygous for the defective FBN1 allele.
D. It is an autosomal disorder.
E. It is a recessive disorder.