what is the mechanism of action of increasing peripheral resistance intervalof verapamil and metoprolol
Verapamil and metoprolol are both medications commonly used to treat high blood pressure and other cardiovascular conditions.
The mechanism of action of verapamil involves blocking calcium channels in the heart and blood vessels, which leads to relaxation of the smooth muscle in the blood vessels and decreased peripheral resistance. This causes the blood vessels to dilate, resulting in decreased blood pressure.
Metoprolol, on the other hand, is a beta-blocker that works by blocking the effects of adrenaline on the heart. This results in a slower heart rate and decreased force of contraction, leading to reduced cardiac output and decreased peripheral resistance in the blood vessels.
Overall, both verapamil and metoprolol work to reduce peripheral resistance in the blood vessels, which helps to lower blood pressure and improve cardiovascular health.