Based on the description provided, the graph that best represents Jamie's scenario is:

C: A coordinate plane graph is shown. The axis is labeled time and the y-axis is labeled distance from home in blocks. A line begins at 0, 8, decreases to 5, 5, decreases again to 8, 3, then stays horizontal to 12, 3. The line decreases to 17, 0.

Here's why:
1. The scenario states that Jamie rode her bike home for 5 blocks, which aligns with the initial decrease from 8 to 5 on the y-axis in graph C.
2. Jamie then realizes she forgot her math book and goes back to school, indicating a movement away from home, represented by the decrease from 5 to 3 on the y-axis.
3. After finding her math book at school, Jamie rides home, leading to a horizontal segment on the graph as she stays at the same distance from home, shown from 8 to 12 on the x-axis and 3 on the y-axis.
4. Finally, the increase from 12 to 17 on the x-axis and from 3 to 0 on the y-axis represents Jamie riding back home after retrieving her math book.

Therefore, graph C best depicts the scenario described with Jamie riding her bike home, realizing she forgot her math book, going back to school, finding the book, and then returning home.

The other two graphs do not accurately represent Jamie's scenario. Graph A shows a constant decrease in distance from home, which does not align with Jamie going back to school after realizing she forgot her math book. Graph B shows a linear decrease in distance from home, which does not capture Jamie's round trip from home to school and back home. Therefore, Graph C is the most appropriate representation of Jamie's scenario.