contact with the Europeans proved to be devastating to the iroquois and hurons. all the bad things took place, which one was the cause of most death among native Americans.

The cause of the most deaths among Native Americans due to contact with Europeans was the introduction of infectious diseases. European diseases, such as smallpox, measles, influenza, and typhus, which had developed resistance among Europeans, were entirely new and highly contagious to Native American tribes. As a result, when these diseases were introduced to the Indigenous populations, they spread rapidly, causing devastating epidemics. The Native Americans had little to no immunity to these diseases, leading to high mortality rates. It is estimated that diseases brought by Europeans wiped out millions of Native Americans in the Americas, including the Iroquois and Hurons.