The main cause of the Great Famine refers to a specific event or historical context is not mentioned in the provided question. The term "Great Famine" can refer to different famines that occurred throughout history. Some prominent examples include the Great Famine in Ireland (1845-1852), caused primarily by a potato blight, and the Great Chinese Famine (1959-1961), which resulted from collectivization policies and the Great Leap Forward campaign. Please provide more information or specify which Great Famine you are referring to.
