5/4 of the 64 musicians in a music contest are guitarists. Some of the guitarists play jazz solos, and the rest play classical solos the ratio of the number of guitarists playing jazz solo to the total number of guitarists in the contest is 1:4 how many guitarists play classical solo in the contest

5/4 of the 64 musicians is equal to (5/4)*64 = <<(5/4)*64=80>>80 guitarists.

If the ratio of the number of guitarists playing jazz solo to the total number of guitarists is 1:4, then the number of guitarists playing jazz solo is 1/(1+4) * 80 = 1/5 * 80 = <<1/5*80=16>>16 guitarists.
The number of guitarists playing classical solo is 80 - 16 = <<80-16=64>>64. Answer: \boxed{64}.