Select all that are disadvantages to sexual reproduction.

1. Sexual reproduction requires the involvement of two individuals, which can be limiting in terms of finding a compatible mate.

2. There is a risk of sexually transmitted infections (STIs) being transmitted between individuals during sexual activity.
3. It takes time and energy to find a mate and engage in courtship behaviors.
4. Sexual reproduction can result in the production of fewer offspring compared to asexual reproduction.
5. There is a risk of genetic recombination and the introduction of harmful mutations during sexual reproduction.
6. Sexual reproduction requires the production and maintenance of specialized reproductive structures.