If you were wearing the sweater shown and rubbed your hand on it, you too would gain some negative charge on your hand. Then when you directly touch a metal conductor, like a door knob, you will feel a shock. This is called Conduction. From this scenario, where does the negative charge go when you touch a door knob?

When you touch a door knob, the negative charge gained from rubbing your hand on the sweater is transferred from your hand to the metal conductor, which in this case is the door knob. The negative charges flow from your body to the door knob, equalizing the charges and creating a brief flow of electric current. This transfer of charge is what causes the sensation of a shock when you touch a door knob after gaining a negative charge.