Silent, missense, and nonsense mutations all characterized by their effect on the resulting:(1 point) Responses Number of base pairs removed Number of base pairs removed Protein shape Protein shape Amino Acid Amino Acid Gene transcription
I'm not sure if I understand your question correctly. Could you please clarify? Are you asking about the effect of silent, missense, and nonsense mutations on the resulting protein?
yes
I see, thank you for clarifying.
Silent mutations are DNA sequence variations that do not result in any change in the amino acid sequence of the resulting protein. They occur when a nucleotide substitution in the DNA sequence does not affect the codon that codes for a particular amino acid. As a result, the protein's primary structure and function remain unaltered.
Missense mutations, on the other hand, result in the substitution of one amino acid for another in the protein sequence. This mutation can potentially alter the protein's structure and function, depending on the specific amino acid change and its location within the protein.
Nonsense mutations are more drastic, as they introduce a premature stop codon into the DNA sequence. This leads to the premature termination of protein synthesis and results in a truncated and usually non-functional protein.
Therefore, silent mutations have no effect on the resulting protein, missense mutations can alter protein structure and function, and nonsense mutations result in the premature termination of protein synthesis, leading to a non-functional protein.
Silent, missense, and nonsense mutations are all characterized by their effect on the resulting amino acid sequence (protein structure).
To understand why, let's break down each type of mutation:
1. Silent mutation: A silent mutation is a type of point mutation where a substitution occurs in the DNA sequence, but it does not result in a change in the corresponding amino acid. This means that there is no impact on the protein structure or function. For example, in the DNA sequence "AAG," a silent mutation may change it to "AAA," but both codes for the same amino acid lysine.
2. Missense mutation: Missense mutations also involve a substitution in the DNA sequence, but this time it results in a change in the corresponding amino acid. This means that the mutation leads to an altered protein structure. For example, a change from "GCC" to "GTC" could lead to the replacement of alanine with valine in the resulting protein.
3. Nonsense mutation: Nonsense mutations are also point mutations, but they introduce a premature stop codon in the DNA sequence. This means that during protein synthesis, the ribosome encounters the stop codon and prematurely terminates the translation process. As a result, a shorter protein is produced, which often lacks functional domains and is non-functional.
In summary, while silent mutations do not affect the protein structure, both missense and nonsense mutations can alter the amino acid sequence and therefore impact the resulting protein's shape and function.