A sentence that has an original statement with quotation marks may also have a comma
Yes, a sentence with a quotation can include a comma, particularly when introducing or ending the quoted material. Here's an example:
Original statement without quotation marks:
Sarah said that she would be late to the meeting.
Same statement with quotation marks and a comma:
Sarah said, "I will be late to the meeting."
In this example, the comma comes after "said" and before the opening quotation mark to set off the quoted statement from the rest of the sentence. Note that the placement of commas in relation to quotation marks can vary between American and British English conventions. In American English, commas and periods are typically placed inside the quotation marks, while in British English, they are placed outside unless they are part of the quoted material.