What is the main difference between prokaryotic and eukaryotic cells?(1 point) Responses Prokaryotes lack a cell membrane on the outside. Prokaryotes lack a cell membrane on the outside. Prokaryotes use RNA instead of DNA. Prokaryotes use RNA instead of DNA. Prokaryotes lack ribosomes to make proteins. Prokaryotes lack ribosomes to make proteins. Prokaryotes lack membrane-bound organelles.

The main difference between prokaryotic and eukaryotic cells is that prokaryotes lack membrane-bound organelles.