Which of the following statements best interprets why the Canton System ended?

Very few countries wanted to use the Canton System.
The Qing Dynasty decided that trading with Europeans was not beneficial.
Europeans refused to see themselves as tributes to the Qing Dynasty.
Europeans’ efforts to avoid Canton System regulations led them to smuggle illegal drugs into China, resulting in war.

Europeans’ efforts to avoid Canton System regulations led them to smuggle illegal drugs into China, resulting in war.