21. Listen to the response and see which would be the best question to ask.

O ¿Dónde esta...?
O ¿De dónde eres?
O¿Cómo estás?
O¿Cómo te llamas?

O ¿Dónde está...?

Based on the response provided, the best question to ask would be "¿Dónde está...?"

To determine the best question to ask based on the given response, it is essential to understand the context and intent behind the response. Here are the translations of the options:

1. ¿Dónde está...? - "Where is...?"
2. ¿De dónde eres? - "Where are you from?"
3. ¿Cómo estás? - "How are you?"
4. ¿Cómo te llamas? - "What is your name?"

The response could be a location, indicating that the best question to ask would be: "¿Dónde está...?" (Where is...?). However, without additional information or context, it is challenging to determine the exact question.