Reem owes her friend $15.25 reem works after school and earns $43.78 after paying her friend that how much money does she have?

Reem has $43.78 - $15.25 = $28.53 after paying her friend. Answer: \boxed{28.53}.

To determine how much money Reem has after paying her friend, we need to subtract the amount she owes from her earnings.

Step 1: Subtract the amount Reem owes from her earnings.
$43.78 - $15.25 = $28.53

Therefore, Reem has $28.53 left after paying her friend.