which of the following is done through science

making aesthetic judgment about nature
explaining supernatural phenomena
refining an educated guess
directing how to apply knowledge

The following is done through science:

- Refining an educated guess
- Directing how to apply knowledge

Out of the options you provided, refining an educated guess and directing how to apply knowledge are done through science.

Refining an educated guess: In the scientific process, hypotheses are formed based on existing knowledge and observations. Through experimentation, data is collected and analyzed to test these hypotheses. The results help refine or modify the original educated guess.

Directing how to apply knowledge: Science helps us understand how to apply knowledge in practical ways. For example, scientific research can lead to the development of technological advancements, medical treatments, and improved agricultural practices. Scientists use their findings to provide guidance on how to apply knowledge to solve real-world problems.

On the other hand, making aesthetic judgments about nature and explaining supernatural phenomena are not typically within the scope of scientific inquiry. Aesthetic judgments are subjective and based on personal preferences and cultural influences, whereas supernatural phenomena often lie outside the realm of scientific testing and observation.