1. A few years later, she even made an organization, Empower Orphans, which sends food, clothes, books, and many other things to orphans.

2. A few years later, she even made an organization, Empower Orphans, and it sends food, clothes, books, and many other things to orphans.
[Does #1 mean #2? Can we change
'which' into 'and it'?]

3. A few years later, she even made an organization, Empower Orphans which sends food, clothes, books, and many other things to orphans.
[In this sentence, ',' is deleted before 'which'. What is the difference between #1 and #3 because of the 'comma' before 'which'?]

1. A few years later, she even founded an organization, Empower Orphans, which sends food, clothes, books, and many other things to orphans.

2. A few years later, she even founded an organization, Empower Orphans, and it sends food, clothes, books, and many other things to orphans.
[Does #1 mean #2? Can we change
'which' into 'and it'?] They mean the same thing, yes, but #2 is wordy. #1 is the better sentence. Note that "made" is not the correct verb for this idea. She founded ... she formed ... she created ... <~~those are better verbs than "made"

3. A few years later, she even founded an organization, Empower Orphans which sends food, clothes, books, and many other things to orphans.
[In this sentence, ',' is deleted before 'which'. What is the difference between #1 and #3 because of the 'comma' before 'which'?] The comma is needed because Empower Orphans is an appositive for the word organization, and an appositive needs a comma before AND AFTER it.
http://www.chompchomp.com/terms/appositive.htm
Scroll down to read about proper punctuation.

#1, #2, and #3 have slight differences in meaning due to the use or omission of certain punctuation marks. Let's break down each sentence and explain the distinctions:

1. "A few years later, she even made an organization, Empower Orphans, which sends food, clothes, books, and many other things to orphans."
In this sentence, the phrase "which sends food, clothes, books, and many other things to orphans" describes the organization "Empower Orphans." The use of commas surrounding "Empower Orphans" sets it off as a non-essential clause. It means that even if the clause was removed, the sentence would still make sense. The inclusion of "which" indicates that the organization itself is responsible for sending aid to orphans.

2. "A few years later, she even made an organization, Empower Orphans, and it sends food, clothes, books, and many other things to orphans."
Sentence #2 is similar to #1, but the word "which" is replaced with "and it." This change suggests that the organization, Empower Orphans, not only exists but also actively sends aid to orphans. It implies a cause-and-effect relationship between the establishment of the organization and its subsequent actions.

3. "A few years later, she even made an organization, Empower Orphans which sends food, clothes, books, and many other things to orphans."
In sentence #3, the comma before "which" is omitted. As a result, the phrase "which sends food, clothes, books, and many other things to orphans" becomes a defining or restrictive clause. It means that the organization "Empower Orphans" is specifically characterized by its activity of sending aid to orphans. Without this clause, the identity of the organization would be incomplete.

To summarize, while all three sentences convey a similar meaning, the inclusion or omission of certain punctuation marks changes the nuances of the sentence. The use of commas and the choice between "which" and "and it" can alter the relationship between Empower Orphans and its activities.