e.g. I missed the history exam. What should I do?
(What does that mean? Did "I" not take the test by mistake or on purpose? What did "I" do?)
We can't tell whether the speaker missed the exam by mistake. We assume he was sick or prevented from taking the exam for a good reason. However, we don't know why he missed the exam.
The speaker is asking for advice, perhaps advice from his teacher. We can assume he wants to make up the exam -- but we don't know.