People with Rhinovirus infections of the nose and throat have an 80-fold increase in kinins and no increase in histamine. What do you expect for rhinoviral symptoms? What disease is caused by rhinoviruses?

Rhinoviral infections typically cause symptoms such as a runny nose, sneezing, coughing, sore throat, and congestion. The increased kinins can also cause inflammation and irritation of the nasal passages, leading to further discomfort. The disease caused by rhinoviruses is commonly known as the common cold.

The increased levels of kinins and no increase in histamine in individuals with Rhinovirus infections of the nose and throat can lead to specific symptoms and are associated with certain diseases.

1. Symptoms of Rhinoviral Infections:
- Runny or stuffy nose
- Sneezing
- Sore throat
- Cough
- Mild headache
- Low-grade fever (in some cases)
- Fatigue or malaise

2. Disease caused by Rhinoviruses:
Rhinoviruses are the main cause of the common cold, also known as acute viral rhinitis. The common cold is a mild respiratory illness that typically affects the nose and throat. Rhinoviruses belong to the Picornaviridae family and are responsible for approximately 30-50% of common cold cases.

Based on the information provided, we can make some predictions about the symptoms of a rhinovirus infection and the disease it causes.

Rhinovirus infections primarily affect the nose and throat, leading to symptoms commonly associated with the common cold. These symptoms can include sneezing, nasal congestion, runny or stuffy nose, sore throat, cough, and mild headache. In some cases, there may also be a low-grade fever or general malaise. It is important to note that these symptoms can vary from person to person and may be milder or more severe depending on individual factors such as immune response.

Histamine is a substance released by the immune system during allergic responses and can cause symptoms such as itching, watery eyes, and hives. Since there is no increase in histamine in individuals with rhinovirus infections, we would not expect to see these typical allergic symptoms.

On the other hand, kinins are a group of substances involved in various physiological processes, including inflammation and pain. With an 80-fold increase in kinins during rhinovirus infections, it is likely that these individuals may experience increased levels of inflammation and discomfort in the nose and throat.

Rhinoviruses are known to primarily cause the common cold, which is a mild respiratory illness. They are one of the main viruses responsible for causing upper respiratory tract infections in humans. It's worth noting that while rhinoviruses are a common cause of the common cold, they are not the only cause. Other viruses, such as coronaviruses, adenoviruses, and respiratory syncytial viruses, can also cause similar symptoms.

In summary, the symptoms you would expect for rhinoviral infections include sneezing, nasal congestion, runny or stuffy nose, sore throat, cough, and possibly a low-grade fever. The disease caused by rhinoviruses is the common cold.