(2^2 • 2^-6)^-3 • (2)^0

To simplify this expression, we first simplify inside the parentheses.

(2^2 • 2^-6)^-3 = (4 • 1/64)^-3 = (4/64)^-3 = (1/16)^-3

Next, we simplify the second part of the expression:

(2)^0 = 1

Putting it all together:

(1/16)^-3 • 1 = (1/(1/16)^3) • 1 = (1/(1/4096)) = 4096

Therefore, the simplified expression is 4096.