Look at Discovery of the Mississippi, a painting showing Hernando de Soto meeting American Indians near the banks of the Mississippi River. Then answer the question that follows.

What was the ultimate outcome of meetings such as the one in the painting?
A.
Many American Indians joined the Spanish and eventually left for Spain.

B.
Many American Indians became Christians and worked to convert others.

C.
Many American Indians were killed by Europeans or died of diseases from Europe.

D.
Many American Indians traded with the Spanish and their quality of life increased.

C. Many American Indians were killed by Europeans or died of diseases from Europe.