Substance dependence, also known as addiction, refers to a condition characterized by a physical and psychological reliance on a drug or substance. Individuals with substance dependence will experience withdrawal symptoms when they stop using the substance, and will often continue to use it despite negative consequences.

Examples of substance dependence include:

1. Alcoholism: Individuals who are dependent on alcohol will experience strong cravings for alcohol, and may continue to drink even when it causes problems in their personal or professional life.

2. Opioid dependence: This can involve dependence on prescription painkillers like oxycodone or illegal drugs like heroin, leading to a dangerous cycle of consumption to prevent withdrawal symptoms.

3. Cocaine addiction: Cocaine is a highly addictive stimulant drug that can lead to dependence, with users experiencing intense cravings and using the drug compulsively despite adverse effects on their health and well-being.

4. Nicotine dependence: Many individuals become addicted to nicotine through smoking cigarettes or using other tobacco products, and may struggle to quit due to withdrawal symptoms and strong cravings.

Overall, substance dependence is a serious medical condition that can have a significant impact on a person's physical, mental, and emotional well-being. Treatment options, such as therapy and medication, can help individuals overcome substance dependence and regain control over their lives.
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Substance dependence, or addiction, refers to a reliance on a drug or substance that results in withdrawal symptoms when stopped and continued use despite negative consequences. Common examples include alcoholism, opioid dependence, cocaine addiction, and nicotine dependence. Treatment options are available to help individuals overcome substance dependence and regain control over their lives.