Determine which of the following expressions are equal to 16. Select all that apply

A. -8 - 8
B. -4 - 12
C. -3 - (-13)
D. -2 - (-18)
E. 2 - (-14)
F. 10 - (-6)

To determine which expressions are equal to 16, we simply calculate each expression:

A. -8 - 8 = -16
B. -4 - 12 = -16
C. -3 - (-13) = -3 + 13 = 10
D. -2 - (-18) = -2 + 18 = 16
E. 2 - (-14) = 2 + 14 = 16
F. 10 - (-6) = 10 + 6 = 16

Therefore, the expressions that equal 16 are D. -2 - (-18), E. 2 - (-14), and F. 10 - (-6).