The relationship between changes in the environment and variations is that changes in the environment can affect the survival and reproduction of organisms with specific variations. Variations in a population may allow certain individuals to better adapt to changes in the environment, leading to their increased survival and reproduction. This can result in natural selection favoring certain variations over others. Over time, this can lead to a change in the frequency of certain variations within a population. Therefore, changes in the environment can influence the distribution of variations in a population through natural selection.