Which mutation scenario will always lead to natural selection?

Responses

a mutation causes a specific variation within the population
a mutation causes a specific variation within the population - no response given

a mutation causes a gene to become inactivated
a mutation causes a gene to become inactivated - no response given

a mutation causes an inactivated gene to be reactivated
a mutation causes an inactivated gene to be reactivated - no response given

a mutation causes a specific advantage within the population

The response "a mutation causes a specific advantage within the population" will always lead to natural selection. This is because individuals with the advantageous mutation will have a higher likelihood of surviving and reproducing, passing on the beneficial trait to future generations. Over time, this can lead to the spread of the advantageous mutation in the population through natural selection.