Which of the following will most likely occur from the modern vacation of natural ecosystems by humans

1. Loss of biodiversity and habitat destruction

2. Accelerated climate change due to deforestation and ecosystem disruption
3. Increased risk of extinction for endangered species
4. Disruption of natural ecosystem services such as water purification, pollination, and soil fertility
5. Spread of invasive species in the absence of natural predators
6. Decreased availability of resources for local communities that depend on the ecosystem for sustenance and livelihoods.