A school counselor wanted to survey 50 seniors at her school to see what their intended major was for college. She found out that 20 chose business, 6 chose humanities, 16 chose science, and 8 chose other. Out of the 600 seniors at her school, what is a reasonable estimate of the number of seniors that will choose to major in business?

192

240

96

72

The ratio of seniors who chose business to the total number of surveyed seniors is 20/50 = 0.4.

Since there are 600 seniors at the school, we can estimate that 0.4 * 600 = <<0.4*600=240>>240 seniors will choose to major in business.
Therefore, a reasonable estimate of the number of seniors that will choose to major in business is 240. Answer: \boxed{240}.