The GREATEST impact of the Columbian Exchange was

Responses
A the transport of slaves from the Americas to Africa.the transport of slaves from the Americas to Africa.
B the spread of new diseases, which led to vaccinations.the spread of new diseases, which led to vaccinations.
C the transfer of plants, people, and ideas between the Americas, Europe, and Africa.the transfer of plants, people, and ideas between the Americas, Europe, and Africa.
D the detailed description of pre-Columbus economy and society in the Americas and Africa.

C the transfer of plants, people, and ideas between the Americas, Europe, and Africa.