Simplify to a single power of 2:

2^2 times 2^4

To simplify the expression 2^2 times 2^4, we can add the exponents since the base is the same (2).

2^2 times 2^4 can be rewritten as 2^(2+4).

Adding the exponents, we get 2^6.

Therefore, 2^2 times 2^4 simplifies to 2^6.