(78^8)^6

To calculate this expression, we will use the exponentiation rule that states that when raising a power to another power, we need to multiply the exponents.

First, we will simplify the expression within the parentheses:
(78^8)^6 = 78^(8*6) = 78^48

Now, we can use a calculator or computer program to find the value of 78^48:

78^48 ≈ 3.451371 * 10^77