What is the ratio 16 to 40 written as a fraction in lowest terms?

1/4

8/20

2/5

3/8

The ratio 16 to 40 can be written as the fraction 16/40. To find the fraction in lowest terms, we can simplify it by dividing both the numerator and the denominator by their greatest common factor, which is 8.

So, 16/40 simplifies to 2/5.

Therefore, the answer is 2/5.