Mrs Lee had $150. She spent 15 percent of the money on groceries, 12 percent of it on a book. How much money had she left?

Mrs Lee spent 15/100 * $150 = $<<15/100*150=22.5>>22.5 on groceries.

She spent 12/100 * $150 = $<<12/100*150=18>>18 on a book.
Thus, Mrs Lee had $150 - $22.5 - $18 = $<<150-22.5-18=109.5>>109.5 left. Answer: \boxed{109.5}.