At two weeks old, the time their critical socialization period begins, wolves can smell but cannot yet see or hear. Domesticated dogs, _ _ can see, hear, and smell by the end of two weeks. This relative lack of sensory input may help explain why wolves behave so differently around humans than dogs do: from a very young age, wolves are more wary and less exploratory.

Which choice completes the text with the most logical transition?
A) in other words,
B) for instance,
C) by contrast,
D) accordingly,

C) by contrast,