Which statement offers the best critique of how humans have impacted the environment through agricultural activities?

Chemicals applied on agricultural crops have led to the lessoning of cultural eutrophication
Humans did not impact the physical environment until the last 150 years
Human agricultural activities have always impacted the physical environment
The agricultural practice of slash and burn does not impact the physical environment in modern times

The statement "Human agricultural activities have always impacted the physical environment" offers the best critique of how humans have impacted the environment through agricultural activities.