Which of the following BEST describes how the Spanish and Hernando DeSoto impacted the Native Americans living in the southeastern region of North America?

A
.

Native Americans benefitted from learning about new technologies from the Europeans.
B.

They formed a strong alliance and became trading partners.
C.

The Native Americans were introduced to new foods.
D.

Thousands of Native Americans died as a result of diseases spread by contact with Europeans.

D. Thousands of Native Americans died as a result of diseases spread by contact with Europeans.