In the election of 1856 Millard Fillmore was the no nothing candidate and received 21% of the popular vote. What conclusion could be drowned from this fact, a significant number of people opposed to slavery? A significant number of people were in favor of temperance? Is significant number of people in favor of women's rights? A significant number of people who were hostile towards immigrants?

A significant conclusion that could be drawn from the fact that Millard Fillmore, the Know-Nothing candidate, received 21% of the popular vote in the election of 1856 is that there was a significant number of people who were hostile towards immigrants. The Know-Nothing Party, also known as the American Party, was primarily focused on anti-immigrant sentiments and aimed to limit the influence of immigrants in American society.