To stop a wound from bleeding, platelets in the blood clump together to form a blood clot. The clot dries into a hard scab to protect the wounded area. Underneath the scab, the blood supplies nutrients and oxygen that help new skin cells form. As the skin regenerates, the wound closes.

Which body systems interact with the integumentary system to close the wound

Circulatory and reproductive
Immune and circulatory
Reproductive and immune
Digestive and endocrine

The correct answer is immune and circulatory systems. The immune system helps to prevent infection in the wounded area, fighting off any pathogens that may enter. The circulatory system supplies nutrients and oxygen to the area, supporting the formation of new skin cells.