What effect did Hernando de Soto's expedition in Georgia have on American Indians there?

Responses
A it caused a mass migration of American Indians from Georgiait caused a mass migration of American Indians from Georgia
B it began a long-term trading relationship with American Indiansit began a long-term trading relationship with American Indians
C it inspired American Indians to join the Spanish mission systemit inspired American Indians to join the Spanish mission system
D it brought illnesses that caused American Indian population l

D

it brought illnesses that caused American Indian population loss