Pepsin is an enzyme produced in the stomach. Pepsin has an optimum pH that is very acidic, between a pH of 1.0 and 2.0. In an experiment involving the enzyme pepsin, the pH is raised from 2 to 11. What will be the MOST LIKELY effect of this on the reaction?

Responses
A The enzyme will denature, stopping the reaction.The enzyme will denature, stopping the reaction.
B The activation energy of the reaction would be reduced.The activation energy of the reaction would be reduced.
C The rate of reaction will reduce due to a decrease in the kinetic energy of the moleculesThe rate of reaction will reduce due to a decrease in the kinetic energy of the molecules
D The rate of reaction will increase due to the increased number of collisions of the enzyme and substrate.

A The enzyme will denature, stopping the reaction.