What type of reaction would 2-bromobutane + hydroxide ion?

The reaction between 2-bromobutane and hydroxide ion would be classified as a nucleophilic substitution reaction, specifically an SN2 (substitution, nucleophilic, bimolecular) reaction. In this reaction, the hydroxide ion acts as a nucleophile, attacking the carbon atom attached to the bromine atom in 2-bromobutane. The bromine atom is then replaced by the hydroxide group, resulting in the formation of butan-2-ol.