prolonged stress may promote illness by depressing the function of the

sympathetic nervous system
parasympathetic nervous system
skeletal nervous system
cardiovascular system
central nervous system

Prolonged stress may promote illness by depressing the function of the immune system and dysregulating the endocrine system. This can ultimately have negative effects on various systems in the body, including:

1. Sympathetic Nervous System: Prolonged stress can lead to overactivation or dysregulation of the sympathetic nervous system, which is responsible for the body's fight-or-flight response. This can result in increased heart rate, elevated blood pressure, and other stress-related physiological responses.

2. Parasympathetic Nervous System: Prolonged stress can also disrupt the function of the parasympathetic nervous system, which is responsible for rest and relaxation. This can prevent the body from properly recovering and rejuvenating, negatively impacting overall health.

3. Skeletal Nervous System: The skeletal nervous system, also known as the somatic nervous system, is responsible for voluntary muscle movement. Prolonged stress can cause muscular tension, pain, and discomfort, which can lead to musculoskeletal disorders and contribute to illness.

4. Cardiovascular System: Chronic stress can lead to persistent activation of the sympathetic nervous system and dysregulation of the cardiovascular system. This can result in increased heart rate, elevated blood pressure, and increased risk of cardiovascular diseases such as hypertension, heart disease, and stroke.

5. Central Nervous System: Prolonged stress can affect the central nervous system, which includes the brain and spinal cord. Chronic stress can lead to changes in brain chemistry and structure, impair cognitive function, and increase the risk of mental health disorders such as anxiety and depression.

Overall, prolonged stress can have profound effects on various bodily systems, leading to increased vulnerability to illness and disease.