Why are common cold viruses difficult to cure?

Vaccines prevent the development of a cure. A copy of the DNA is made from the viral RNA.
The virus leads to other viral infections such as the flu and HIV.
The viral genome mutates very quickly.

Common cold viruses are difficult to cure due to several reasons:

1. Lack of effective antiviral drugs: Currently, there are no specific antiviral drugs available that can effectively target and eliminate common cold viruses. This is partly because developing drugs targeting such viruses is challenging due to their complex structure and biology.

2. Rapid mutation rate: Common cold viruses have a high rate of genetic mutation or variation. This means that the genetic material (RNA) of these viruses can change quickly and produce new strains that can evade the immune system or become resistant to treatments. This makes it difficult to develop a single cure that can target all variants of the virus.

3. Diversity of cold viruses: The common cold is caused by several different types of viruses, including rhinoviruses, coronaviruses, and respiratory syncytial viruses, among others. Each of these viruses has unique characteristics and features, making it challenging to develop a universal cure to target all types.

4. Host immune response: The common cold primarily affects the upper respiratory tract, where the immune response may not be as strong as in other parts of the body. This allows the virus to replicate and spread before the immune system mounts an effective defense. Additionally, the immune response to the common cold is generally mild, and the virus often develops mechanisms to evade and manipulate the immune system, making it difficult to clear the infection.

5. Lack of long-lasting immunity: Even if someone successfully recovers from a common cold infection, they can get reinfected with the same or different strains in the future. This is because the immunity developed after a cold infection is often temporary and does not provide long-lasting protection against subsequent infections.

It is worth noting that vaccines primarily aim to prevent common cold infections by inducing an immune response against specific strains of viruses, rather than curing ongoing infections.