DDX for unilateral thigh swelling of 2 weeks duration
There are several potential causes for unilateral thigh swelling of 2 weeks duration. The differential diagnosis can include:
1. Deep vein thrombosis (DVT): Blood clot formation in the deep veins of the leg can cause swelling and pain. Risk factors for DVT include prolonged immobility, recent surgery, pregnancy, obesity, and history of blood clotting disorders.
2. Cellulitis: This is a bacterial infection of the skin and underlying tissues, which can cause redness, warmth, swelling, and tenderness in the affected area.
3. Lymphedema: This is a condition characterized by the accumulation of lymph fluid, often caused by damage or blockage of the lymphatic system. It can cause swelling in one limb, typically the leg.
4. Musculoskeletal injury: A fracture, sprain, or strain in the thigh muscles or bones can cause localized swelling, pain, and limited range of motion.
5. Baker's cyst: This is a fluid-filled swelling that develops behind the knee joint, which can sometimes extend down into the calf or up into the thigh causing unilateral swelling.
6. Peripheral artery disease (PAD): Reduced blood flow to the leg arteries can cause pain, cramping, and swelling in the affected leg. Risk factors for PAD include smoking, diabetes, high blood pressure, and high cholesterol.
7. Lipedema: A condition characterized by abnormal fatty deposits in the legs, commonly affecting women. It can cause pain, swelling, and tenderness in the thighs.
8. Inflammatory conditions: Conditions such as vasculitis, lupus, or rheumatoid arthritis can cause inflammation and swelling in the thighs.
9. Systemic causes: Conditions like heart failure, kidney disease, or liver disease can lead to fluid retention and swelling in the lower extremities.
It is important to consult a healthcare professional for a proper evaluation, physical examination, and any necessary investigations to determine the underlying cause of the thigh swelling.