Why did the American colonists want to Spain control into the Ohio valley in the mid 1700s

The American colonists did not want Spain to control the Ohio Valley in the mid-1700s. Instead, they wanted to expand their own territory and gain control over the Ohio Valley. The Ohio Valley was a region rich in natural resources and fertile land, making it an attractive prospect for the colonists who sought to secure economic opportunities and grow their settlements. Additionally, control over the Ohio Valley would provide a strategic advantage in the ongoing struggles between British and French interests in North America. Therefore, the colonists were motivated to challenge and ultimately limit Spanish control in the region.